34586-43-1Relevant academic research and scientific papers
Nitrene transfer catalyzed by a non-heme iron enzyme and enhanced by non-native small-molecule ligands
Goldberg, Nathaniel W.,Knight, Anders M.,Zhang, Ruijie K.,Arnold, Frances H.
supporting information, p. 19585 - 19588 (2019/12/24)
Transition-metal catalysis is a powerful tool for the construction of chemical bonds. Here we show that Pseudomonas savastanoi ethylene-forming enzyme, a non-heme iron enzyme, can catalyze olefin aziridination and nitrene C-H insertion, and that these activities can be improved by directed evolution. The non-heme iron center allows for facile modification of the primary coordination sphere by addition of metal-coordinating molecules, enabling control over enzyme activity and selectivity using small molecules.
Enantioselective intramolecular benzylic C-H bond amination: Efficient synthesis of optically active benzosultams
Ichinose, Masami,Suematsu, Hidehiro,Yasutomi, Yoichi,Nishioka, Yota,Uchida, Tatsuya,Katsuki, Tsutomu
supporting information; experimental part, p. 9884 - 9887 (2011/12/02)
'Salen' along: The iridium(III)-salen complex 1 efficiently catalyzes the title reaction of 2-ethylbenzenesulfonyl azides to give five-membered sultams with high enantioselectivity. Other 2-alkyl-substitued substrates lead to five- and six-membered sultam
Endothelin receptor antagonists
-
, (2008/06/13)
Novel compounds of the formula I STR1 in which R 1, R 2, R 3, --A B--C D--, Ar and X have the meaning indicated in claim 1, and their salts show endothelin receptor-antagonistic properties.
CATALYTIC SULFONYLATION OF PHENOL BY STERICALLY HINDERED SULFONYL CHLORIDES
Vizgert, R.V.,Maksimenko, N.N.,Rubleva, L.I.
, p. 2144 - 2146 (2007/10/02)
The sulfonylation of phenol by substituted arenesulfonyl chlorides XArSO2Cl in the presence of triethylamine in benzene was studied by potentiometric titration.A linear relation was obtained between the logaritmhs of the catalytic rate constants and the steric constants Eso of the substituents in the sulfonyl chloride.The contribution from the induction and steric effects of the substituents at position2 to the kinetics of the process was assessed.It was concluded that the steric effect plays a predominant role over the induction and resonance effects.
