345938-48-9Relevant academic research and scientific papers
The heterocyclic ring of 4-substituted-1,8-naphthalimides is NOT inert to nucleophilic attack, contrary to earlier reports
McKenney, Ryan K.,Groess, Leah L.,Kopidlansky, Kyle M.,Dunkle, Kelsey L.,Lewis, David E.
, p. 4390 - 4396 (2013)
The heterocyclic ring of N-aryl-4-chloro-1,8-naphthalimides, reported to be resistant to nucleophilic attack, reacts with primary amine nucleophiles at room temperature to give 4-chloro-N-alkyl-1,8-naphthalimides. The reaction is first order in the naphth
METHODS AND COMPOSITIONS FOR TREATING BETA-THALASSEMIA AND SICKLE CELL DISEASE
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Paragraph 0221; 0222; 228, (2016/05/19)
Compounds, pharmaceutical compositions, and methods for treating anemia β-thalassemia anemia or sickle cell anemia.
Methods and compositions for treating beta-thalassemia and sickle cell disease
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Paragraph 0289; 0290; 0291; 0292; 0303; 0304, (2016/10/08)
Compounds, pharmaceutical compositions, and methods for treating anemia beta-thalassemia anemia or sickle cell anemia are disclosed.
