345938-52-5Relevant academic research and scientific papers
Palladium-catalyzed three-component cascade arylthiolation with aryldiazonium salts asS-arylation sources
Li, Jianxiao,Tang, Hao,Lin, Zidong,Yang, Shaorong,Wu, Wanqing,Jiang, Huanfeng
, p. 4071 - 4078 (2020)
A novel and efficient palladium-catalyzed three-component cascade cyclization/arylthiolation has been developed for the assembly of diverse 3-sulfenylindole and 3-sulfenylbenzofuran derivatives from 2-alkynylamines and 2-alkynylphenols, aryldiazonium salts, and Na2S2O3under aerobic conditions with PEG-200 as an environmentally benign medium. The current study features exceptional functional group tolerance without additional ligands, oxidants or silver salts, and eco-friendly mild reaction conditions. The ionic liquid [C2OHmim]Cl plays a crucial role in this protocol as an environmentally friendly additive. Notably, this procedure represents the first example of the use of aryldiazonium salts as directS-arylation sources in this type of chemical transformation.
PdCl2-promoted electrophilic annulation of 2-alkynylphenol derivatives with disulfides or diselenides in the presence of iodine
Du, Hui-Ai,Zhang, Xing-Guo,Tang, Ri-Yuan,Li, Jin-Heng
experimental part, p. 7844 - 7848 (2010/01/16)
(Chemical Equation Presented) An efficient synthesis of 3-chalcogen-benzo[b]furans via palladium-promoted annulation reactions of 2-alkynylphenol derivatives with disulfides or diselenides and iodide has been developed. In the presence of I2 an
