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3,3',5-Triiodo-L-thyronine (T3) sodium salt is a synthetic form of the naturally occurring thyroid hormone, 3,3',5-triiodo-L-thyronine. It is produced through the monodeiodination of the prohormone thyroxine (T4) in various tissues, such as the liver and kidney. T3 sodium salt acts as an agonist for thyroid hormone receptors TRα and TRβ, playing a crucial role in regulating various biological properties, including metabolism, cardiac function, growth, and redox signaling. Additionally, it serves as an inhibitor of L-type amino acid transporter 1 (LAT1), blocking LAT1-mediated leucine uptake in certain cell lines.

345957-19-9

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345957-19-9 Usage

Uses

Used in Pharmaceutical Industry:
3,3',5-Triiodo-L-thyronine sodium salt is used as a therapeutic agent for treating various thyroid-related disorders. Its application is based on its ability to modulate metabolism, cardiac function, growth, and redox signaling, making it a valuable compound in managing conditions such as hypothyroidism and certain metabolic issues.
Used in Research and Development:
In the field of research, 3,3',5-triiodo-L-thyronine sodium salt is utilized as a research tool to study the effects of thyroid hormones on cellular processes and the underlying mechanisms of action. Its role as an inhibitor of L-type amino acid transporter 1 (LAT1) also makes it a valuable compound for investigating the transport of amino acids in cells.
Used in Diagnostic Applications:
3,3',5-Triiodo-L-thyronine sodium salt can be employed in diagnostic tests to assess thyroid function and monitor the effectiveness of treatments for thyroid-related conditions. Its ability to interact with thyroid hormone receptors and modulate biological properties makes it a useful marker for evaluating thyroid status in patients.

Check Digit Verification of cas no

The CAS Registry Mumber 345957-19-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,5,9,5 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 345957-19:
(8*3)+(7*4)+(6*5)+(5*9)+(4*5)+(3*7)+(2*1)+(1*9)=179
179 % 10 = 9
So 345957-19-9 is a valid CAS Registry Number.

345957-19-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophen yl]propanoate hydrate (1:1:1)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:345957-19-9 SDS

345957-19-9Upstream product

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