34611-07-9

Basic information

• Product Name: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE
• Synonyms: Propylamine,2,2-diphenyl- (6CI,8CI); 2,2-Diphenylpropan-1-amine; 2,2-Diphenylpropylamine
• CAS NO: 34611-07-9
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 0
• Mol File: 34611-07-9.mol

Chemical Properties

• Boiling Point: 328.1°Cat760mmHg
• Flash Point: 152.7°C
• Appearance: /
• Density: 1.023g/cm³
• CAS DataBase Reference: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE(34611-07-9)
• EPA Substance Registry System: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE(34611-07-9)

Safety Data

• Hazardous Substances Data: 34611-07-9(Hazardous Substances Data)

Upstream product

• 5558-67-8 2,2-diphenylpropionitrile 
• 86-29-3 Diphenylacetonitrile 

Downstream Products

• 37391-19-8 3-methyl-3-phenylindoline 
• 1219624-72-2 N-(2,2-diphenylpropyl)-2-(2-oxo-3,3-diphenylpiperidin-1-yl)acetamide 
• 1219624-46-0 2-[3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl]-N-(2,2-diphenylpropyl)acetamide 
• 1219623-60-5 N-(2,2-diphenylpropyl)-2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetamide 
• 90530-64-6 2,2'-[(2,2-Diphenylpropyl)imino]bis[ethanol]Hydrochloride 
• 98383-65-4 N₆-(2,2-Diphenylpropyl)-2-aminoadenosine 

Relevant articles and documents

Investigation of the mechanism of decyanation of 2,2-diphenylpropionitrile induced by LiAlH4

The LiAlH4 reduction of 2,2-diphenylpropionitrile (4) in THF yields a mixture of the hycrocarbon 6 and the expected amine 5. Medium effects and reduction with LiAID4 suggest a mechanism involving the attack of the hydride reagent on the cyano carbon atom followed by the fragmentation of the formed imine salt intermediate. Copyright

SUMO INHIBITOR COMPOUNDS AND USES THEREOF

The present invention relates to compounds and compositions capable of acting as inhibitors of small ubiquitin-like modifier (SUMO) family of proteins. The compounds and compositions may be used in the treatment of cancer. There are disclosed, inter alia, methods of inhibiting an E1 enzyme, and compounds useful for inhibiting an E1 enzyme.

Synthesis of indolines by copper-mediated intramolecular aromatic C-H amination

A Cu(OAc)2-mediated intramolecular aromatic C-H amination proceeds with the aid of a picolinamide-type bidentate coordination group to deliver the corresponding indolines in good yields. The reaction occurs smoothly even under noble-metal-free conditions, and in some cases the use of an MnO2 terminal oxidant renders the process catalytic in Cu. The mild oxidation aptitude of Cu(OAc)2 and/or MnO2 accommodates the formation of electron-rich thiophene-and indole-fused indoline analogues. The Cu-based system can provide an effective approach to various indolines of potent interest in pharmaceutical and medicinal chemistry.

First Observation of a C-CN Bond cleavage During the Reduction of a Nitrile with LiAlH4: a S.E.T. Reaction?

LiAlH4 reduction of 5-cyano-5-isopropylsulphonylnorborn-2-ene 1 gave the reduced product 2 resulting from the first reported LiAlH4-induced C-CN bond cleavage.Preliminary observations suggest that the first step involves a S.E.T. (Single Electron Transfer).