34637-54-2Relevant academic research and scientific papers
Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110α inhibitors
Hayakawa, Masahiko,Kaizawa, Hiroyuki,Moritomo, Hiroyuki,Koizumi, Tomonobu,Ohishi, Takahide,Okada, Minoru,Ohta, Mitsuaki,Tsukamoto, Shin-ichi,Parker, Peter,Workman, Paul,Waterfield, Mike
, p. 6847 - 6858 (2007/10/03)
A series of 4-morpholino-2-phenylquinazolines and related derivatives were prepared and evaluated as inhibitors of PI3 kinase p110α. In this series, the thieno[3,2-d]pyrimidine derivative 15e showed the strongest inhibitory activity against p110α, with an
