34650-66-3

Usage

Uses

Used in Pharmaceutical and Chemical Research:
1-Propanone, 2-bromo-1-cyclopropyl(9CI) is utilized as a building block for the synthesis of various organic compounds, making it a valuable asset in the development of new pharmaceuticals and other chemical products. Its unique structure and reactivity allow for the creation of diverse molecules with potential applications in medicine and other industries.
Used as a Reagent in Organic Chemistry:
In the realm of organic chemistry, 1-Propanone, 2-bromo-1-cyclopropyl(9CI) serves as a reagent for the preparation of other compounds. Its ability to participate in various chemical reactions facilitates the synthesis of a wide range of organic molecules, broadening its utility in research and development.
Used in Medicinal Chemistry:
Due to its structural features and reactivity, 1-Propanone, 2-bromo-1-cyclopropyl(9CI) holds potential for use in medicinal chemistry. Researchers in the field of drug discovery and development are interested in 1-Propanone, 2-bromo-1-cyclopropyl- (9CI) as it may contribute to the creation of new therapeutic agents.
It is crucial to handle 1-Propanone, 2-bromo-1-cyclopropyl(9CI) with care, as it may pose potential hazards to human health and the environment. Proper safety measures should be implemented during its use to mitigate any risks associated with 1-Propanone, 2-bromo-1-cyclopropyl- (9CI).

Upstream product

• 6704-19-4 1-cyclopropylpropan-1-one 

Downstream Products

• 1434589-11-3 C₂₀H₂₁N₇O 
• 1447910-76-0 N-(1-(1-cyclopropyl-1-oxopropan-2-yl)-5-iodopyridin-2(1H)-ylidene)-4-methylbenzenesulfonamide 
• 1447913-61-2 N-(5-bromo-1-(1-cyclopropyl-1-oxopropan-2-yl)pyrazin-2(1H)-ylidene)-4-methylbenzenesulfonamide 
• 1447913-60-1 4-((4-chlorobenzyl)oxy)-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyrazin-6-yl)pyridin-2(1H)-one 
• 1447913-74-7 4-((4-chlorobenzyl)oxy)-1-(2-cyclopropyl-3-methylimidazo[1,2-b]pyridazin-6-yl)pyridin-2(1H)-one 
• 1459803-71-4 C₂₄H₃₂N₄O₅S 
• 1459803-38-3 C₂₀H₂₅N₃O₃S 
• 1447913-77-0 4-((4-chlorobenzyl)oxy)-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyrimidin-6-yl)pyridin-2(1H)-one 
• 1447911-95-6 4-((4-chlorobenzyl)oxy)-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyrimidin-2(1H)-one 
• 1447910-88-4 6-((4-chlorobenzyl)oxy)-3-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyrimidin-4(3H)-one 
• 1447911-76-3 5-((4-chlorobenzyl)oxy)-2-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridazin-3(2H)-one 
• 1447910-84-0 1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-((4-(trifluoromethyl)benzyl)oxy)pyridin-2(1H)-one 
• 1447913-67-8 1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-{[4-(propan-2-yl)benzyl]oxy}pyridin-2(1H)-one 
• 1447913-68-9 4-((4-bromobenzyl)oxy)-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one 

Relevant academic research and scientific papers

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

CXCR4 Receptor Antagonists

Disclosed are compounds that are antagonists of the CXCR4 receptor.

CXCR4 RECEPTOR ANTAGONISTS

The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.

Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists

A series of imidazo[1,2-a]pyridine derivatives was identified and evaluated for MCH1R binding and antagonistic activity. Introduction of a methyl substituent at the 3-position of imidazo[1,2-a]pyridine provided compounds with a significant improvement in MCH1R affinity. Representative compounds in this series exhibited good potency and brain exposure in rats.