3466-23-7 Usage
Description
Dehydrodeguelin, a natural product from the rotenoid class of compounds, is derived from the plant species Tephrosia vogelii. It is recognized for its diverse pharmacological activities, such as anti-cancer, anti-inflammatory, and anti-oxidant properties. Dehydrodeguelin has demonstrated inhibitory effects on various cancer cell lines, making it a promising candidate for cancer therapy. Furthermore, it exhibits anti-inflammatory activity by suppressing the production of inflammatory mediators and reducing the expression of inflammatory genes. Its anti-oxidant properties contribute to the protection of cells from oxidative damage, thus promoting overall cellular health. Dehydrodeguelin's potential for various therapeutic applications is currently a focus of research in the field of natural products and pharmacology.
Uses
Used in Pharmaceutical Industry:
Dehydrodeguelin is used as a potential anti-cancer agent for its ability to inhibit the growth of various cancer cell lines, making it a candidate for cancer therapy.
Used in Anti-Inflammatory Applications:
Dehydrodeguelin is used as an anti-inflammatory agent due to its capacity to inhibit the production of inflammatory mediators and reduce the expression of inflammatory genes, thereby helping to manage inflammation.
Used in Anti-Oxidant Formulations:
Dehydrodeguelin is used as an anti-oxidant in formulations designed to protect cells from oxidative damage, contributing to the promotion of overall cellular health.
Check Digit Verification of cas no
The CAS Registry Mumber 3466-23-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,6 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3466-23:
(6*3)+(5*4)+(4*6)+(3*6)+(2*2)+(1*3)=87
87 % 10 = 7
So 3466-23-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H20O6/c1-23(2)8-7-12-15(29-23)6-5-13-21(24)20-14-9-17(25-3)18(26-4)10-16(14)27-11-19(20)28-22(12)13/h5-10H,11H2,1-4H3
3466-23-7Relevant articles and documents
Structural elucidation and chemical conversion of amorphispironone, a novel spironone from Amorpha fruticosa, to rotenoids
Terada,Kokumai,Konoshima,Kozuka,Haruna,Ito,Estes,Li,Wang,Lee
, p. 187 - 190 (2007/10/02)
To search for possible antitumor promoters, we carried out an investigation of the leaves of Amorpha fruticosa L. (Leguminosae). The novel spironone type rotenoid, amorphispironone (1), was isolated together with four known rotenoids, tephrosin (2), amorphigenin (3), 12a-hydroxyamorphigenin (4) and 12a-hydroxydalpanol (5). Some of these compounds were inhibitors of Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol-13-acetate. The structure of 1 was determined from 2D-NMR spectral data and difference NOE experiments. Amorphispironone (1) was also converted to known rotenoids in order to confirm the proposed structure.
