34662-28-7

Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-2-nitrobenzonitrile is used as a key intermediate in the production of 2-aminopyridine, which is essential for the manufacturing of various pharmaceuticals. Its presence in the synthesis process contributes to the development of new and effective medications.
Used in Agrochemical Industry:
3-Chloro-2-nitrobenzonitrile is utilized as an intermediate in the synthesis of pesticides and herbicides. Its incorporation in these products helps enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used in Dye Industry:
3-Chloro-2-nitrobenzonitrile serves as a building block in the creation of various dyes. Its chemical properties allow for the development of dyes with unique color characteristics and improved performance in different applications.
Safety Precautions:
Due to its hazardous nature, 3-Chloro-2-nitrobenzonitrile should be handled with care to avoid irritation to the skin, eyes, and respiratory system. Proper safety measures, such as wearing protective gear and working in well-ventilated areas, should be taken to minimize potential health risks.

Upstream product

• 59772-47-3 3-chloro-2-nitrobenzamide 
• 4771-47-5 3-chloro-2-nitro-benzoic acid 

Downstream Products

• 1196131-20-0 C₁₁H₁₃N₃O₂ 
• 1437790-12-9 3-((4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)cyclohexyl)amino)-2-nitrobenzonitrile 
• 1456507-29-1 2-amino-3-(((1r,4r)-4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)cyclohexyl)amino)benzonitrile 
• 1456507-28-0 3-(((1r,4r)-4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)cyclohexyl)amino)-2-nitrobenzonitrile 

Relevant academic research and scientific papers

Synthesis and potent antifungal activity against Candida species of some novel 1H-benzimidazoles

(Chemical Equation Presented) A series of 47 novel N1-alkylated- 2-aryl-5(6)-substituted-1H-benzimidazoles and their three novel indole analogues were synthesized and evaluated for in vitro antifungal activities against Candida species by the tube dilution method. The results showed that compounds 79 and 80, having pyridine at the position C-2, of benzimidazoles exhibited the greatest activity with MIC values of 6.25-3.12 μg/mL. Indole analogues 108-110 have no inhibitory activity.

Use of EP4 receptor ligands in the treatment of IL-6 involved diseases

Methods of treating IL-6 involved diseases with EP4 receptor ligands, including EP4 receptor antagonists. Assays to determine the effect of test compounds on PGE2-induced whole blood cells activation.

EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS

The invention features a method of treating rheumatoid arthritis in a mammal comprising administering an agent that inhibits prostaglandin EP4 receptor (EP4) activity. Also featured is a method of identifying agents that selectively inhibit EP4 activity in vivo.

Relaxation of smooth muscle in a mammal

4-Amino-6-arylpyrimidines and salts thereof, a novel class of inhibitors of platelet aggregation and broncho-dilators in mammals, and 4-hydroxy-6-arylpyrimidines as useful intermediates.