346664-41-3Relevant academic research and scientific papers
Structure-activity relationship in the oxazolidinone-quinolone hybrid series: Influence of the central spacer on the antibacterial activity and the mode of action
Hubschwerlen, Christian,Specklin, Jean-Luc,Baeschlin, Daniel K.,Borer, Yves,Haefeli, Sascha,Sigwalt, Christine,Schroeder, Susanne,Locher, Hans H.
, p. 4229 - 4233 (2007/10/03)
Oxazolidinone-quinolone hybrids, which combine the pharmacophores of a quinolone and an oxazolidinone, were synthesised and shown to be active against a variety of susceptible and resistant Gram-positive and Gram-negative bacteria. The nature of the space
