34667-29-3Relevant academic research and scientific papers
Synthesis of phospholes and 1,1′-biphospholes mediated by zirconacyclopentadienes and PBr3
Qin, Chunxiang,Xie, Xin,Wang, Gaonan,Jia, Xueshun,Liu, Yuanhong
supporting information, (2019/12/24)
The efficient synthesis of phospholes through the reactions of Grignard reagents with in situ-generated 1-bromophospholes has been developed. This method allows the easy substituent variation at the phosphorus atom of the phospholes. The 1,1′-biphospholes can also be conveniently prepared through Zn-promoted debromo-dimerization of 1-bromophospholes. The gold-phosphole complexes of LAuCl were also synthesized, which were found to act as efficient catalysts in gold-catalyzed [3+2] cycloaddition of ynamides with 4,5-dihydro-1,2,4-oxadiazoles.
