346690-97-9

Basic information

• Product Name: Carbamic acid, (1-formylpropyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (1-formylpropyl)-, 1,1-dimethylethyl ester (9CI);tert-butyl 1-oxobutan-2-ylcarbamate;Carbamic Acid, (1-Formylpropyl)-, 1,1-Dimethylethyl Ester
• CAS NO: 346690-97-9
• Molecular Formula: C₉H₁₇NO₃
• Molecular Weight: 187.23618
• Product Categories: N-BOC
• Mol File: 346690-97-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 266.5±23.0 °C(Predicted)
• Appearance: /
• Density: 1.000±0.06 g/cm3(Predicted)
• PKA: 11.43±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, (1-formylpropyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (1-formylpropyl)-, 1,1-dimethylethyl ester (9CI)(346690-97-9)
• EPA Substance Registry System: Carbamic acid, (1-formylpropyl)-, 1,1-dimethylethyl ester (9CI)(346690-97-9)

Safety Data

• Hazardous Substances Data: 346690-97-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 193086-15-6 (1-(hydroxymethyl)propyl)carbamic acid tert-butyl ester 
• 58561-08-3 methyl N-(tert-butoxycarbonyl)-2-aminobutyrate 

Downstream Products

• 304021-07-6 tert-butyl ((3R)-2-hydroxypentan-3-yl)carbamate 

Relevant articles and documents

CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT

Compounds of Formula (I) or (X) are provided including for treatment of disorders such as a disorder or symptom associated with neuronal cell death. In one aspect, compounds which are selective inhibitors of calpain-2 are provided. Preferred compounds can

Synthesis of proline analogues as potent and selective cathepsin S inhibitors

Cathepsin S is a potential target of autoimmune disease. A series of proline derived compounds were synthesized and evaluated as cathepsin S inhibitors. We discovered potent cathepsin S inhibitors through structure-activity relationship studies of proline analogues. In particular, compound 19-(S) showed promising in vitro/vivo pharmacological activities and properties as a selective cathepsin S inhibitor.

TRPV3 Modulators

Disclosed herein are modulators of TRPV3 of formula (I) wherein X1, X2, R1, R2, Rx, and n are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.