346728-97-0

Basic information

• Product Name: 1-(4-Chloro-3-trifluoromethyl-phenyl)-4-propyl-piperazine
• Synonyms: 1-(4-Chloro-3-trifluoromethyl-phenyl)-4-propyl-piperazine
• CAS NO: 346728-97-0
• Molecular Weight: 306.759
• Mol File: 346728-97-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-Chloro-3-trifluoromethyl-phenyl)-4-propyl-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chloro-3-trifluoromethyl-phenyl)-4-propyl-piperazine(346728-97-0)
• EPA Substance Registry System: 1-(4-Chloro-3-trifluoromethyl-phenyl)-4-propyl-piperazine(346728-97-0)

Safety Data

• Hazardous Substances Data: 346728-97-0(Hazardous Substances Data)

Upstream product

• 21867-64-1 1-n-propylpiperazine 
• 445-01-2 5-bromo-2-chlorobenzotrifluoride 

Relevant articles and documents

Modulators of dopamine neurotransmission

New substituted 4-phenyl N-alkyl)-piperazine and 4-phenyl-N-alkyl)-piperidine compounds of Formula (1) wherein X is N, CH, or C, however X may only be C when the compound comprises a double bind at the dotted line; R1 is CF3, OSO2CF3, OSO2CH3, SOR7, SO2R7, COR7, CN, OR3, NO2, CONHR3, 3-thiophene, 2-thiophene, 3-furane, 2-furane, F, Cl, Br, or I; R2 is F, Cl, Br, I, CN, CF3, CH3, OCH3, OH, and NH2; R3 and R4 are independently H or a C1-C4 alkyl; R5 is a C1-C4 alkyl, an allyl, CH2SCH3, CH2CH2OCH3, CH2CH2CH2F, CH2CF3, 3,3,3-trifluoropropyl, 4,4,4-trifluorobutyl, or —(CH2)—R6; R6 is a C3-C6 cycloalkyl, 2-tetrahydrofurane, or 3-tetrahydrofurane; R7 is a C1-C3 alkyl, CF3, or N(R4)2, and pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed.