34684-19-0 Usage
Description
1,2-Cyclohexanedicarbonyl dichloride (9CI) is a chemical compound with the molecular formula C8H10Cl2O2. It is a colorless liquid with a pungent odor and is mainly used in the production of polymers and plastics. This chemical is classified as an intermediate in the manufacturing of pharmaceuticals, agrochemicals, and specialty chemicals. It is a reactive compound that can undergo various chemical reactions, including nucleophilic substitution and condensation with amines and alcohols.
Uses
Used in Polymer and Plastics Industry:
1,2-Cyclohexanedicarbonyl dichloride (9CI) is used as a monomer for the production of polymers and plastics. Its reactive nature allows it to undergo various chemical reactions, making it a valuable component in the synthesis of these materials.
Used in Pharmaceutical Industry:
1,2-Cyclohexanedicarbonyl dichloride (9CI) is used as an intermediate in the manufacturing of pharmaceuticals. Its ability to undergo nucleophilic substitution and condensation reactions with amines and alcohols makes it a useful building block for the synthesis of various drug compounds.
Used in Agrochemical Industry:
1,2-Cyclohexanedicarbonyl dichloride (9CI) is used as an intermediate in the production of agrochemicals. Its reactivity and ability to participate in chemical reactions contribute to the development of effective agricultural chemicals.
Used in Specialty Chemicals Industry:
1,2-Cyclohexanedicarbonyl dichloride (9CI) is used as an intermediate in the manufacturing of specialty chemicals. Its versatility in chemical reactions allows it to be incorporated into a wide range of specialized chemical products.
Safety Precautions:
1,2-Cyclohexanedicarbonyl dichloride (9CI) is considered hazardous, and proper safety precautions should be taken when handling and storing this chemical. It is essential to follow all safety guidelines and regulations to minimize the risk of exposure and potential harm.
Check Digit Verification of cas no
The CAS Registry Mumber 34684-19-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,6,8 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 34684-19:
(7*3)+(6*4)+(5*6)+(4*8)+(3*4)+(2*1)+(1*9)=130
130 % 10 = 0
So 34684-19-0 is a valid CAS Registry Number.
34684-19-0Relevant articles and documents
Novel bivalent securinine mimetics as topoisomerase I inhibitors
Hou, Wen,Lin, Hui,Wang, Zhen-Ya,Banwell, Martin G.,Zeng, Ting,Sun, Ping-Hua,Lin, Jing,Chen, Wei-Min
, p. 320 - 328 (2017/03/08)
A series of novel bivalent securinine mimetics incorporating different linkers between C-15 and C-15′ were synthesized and their topoisomerase I (Topo I) inhibitory activities evaluated. It was thus revealed that mimetic R2 incorporating a rigid m-substituted benzene linker exhibits Topo I inhibitory activity three times that of parent securinine. Comprehensive structure-activity relationship analyses in combination with docking studies were used to rationalize the potent activity of these bivalent mimetics. Mechanistic studies served to confirm the deductions arising from docking studies that the active bivalent mimetics not only inhibited complexation between Topo I and DNA but also stabilized the Topo I-DNA complex itself.