34688-70-5

Usage

Uses

Used in Pharmaceutical Industry:
PENTAMETHYLPHENYLACETONITRILE is used as a building block for the production of pharmaceuticals. Its compatibility with functional groups and versatile reactivity make it instrumental in the development of new medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, PENTAMETHYLPHENYLACETONITRILE is utilized as an intermediate, contributing to the synthesis of various agrochemicals that aid in crop protection and enhancement of agricultural yields.
Used in Fragrance Industry:
PENTAMETHYLPHENYLACETONITRILE is employed as a key component in the creation of fragrances, leveraging its ability to contribute to the development of novel and complex scent profiles.
Used in Dye and Pigment Manufacturing:
This chemical compound is also used in the manufacturing of dyes and pigments, where its reactivity and properties are harnessed to produce a wide array of colorants for various applications.

InChI:InChI=1/C13H17N/c1-8-9(2)11(4)13(6-7-14)12(5)10(8)3/h6H2,1-5H3

Upstream product

• 484-65-1 2,3,4,5,6-pentamethylbenzyl chloride 
• 151-50-8 potassium cyanide 
• 700-12-9 pentamethylbenzene, 
• 143-33-9 sodium cyanide 

Downstream Products

• 76935-70-1 2,3,4,5,6-pentamethyl-phenethylamine 
• 53546-75-1 Pentamethylphenylacetic Acid 
• 116876-72-3 3-(Pentamethylphenyl)propanenitrile 
• 92622-90-7 2-(2,3,4,5,6-pentamethylphenyl)ethanol 
• 92622-89-4 ethyl(2,3,4,5,6-pentamethylphenyl)acetate 

Relevant academic research and scientific papers

FRIEDEL-CRAFTS CHLOROETHYLATION OF HEXAMETHYLBENZENE

The reaction of hexamethylbenzene (I) with 1,2-dichloroethane in the presence of aluminium chloride gives 1-(2-chloroethyl)-1,2,3,4,5,6-hexamethylbenzenium salt (II) which is decomposed with water.The decomposition products include hexamethylbenzene (I),

OXIDATION OF HEXAMETHYLBENZENE AND 2,3,4,5,6-PENTAMETHYLBENZYL CATION IN FLUOROSULFONIC ACID

The oxidation of hexamethylbenzene in HSO3F-PbO2 takes place with the participation of the 1-H+-1,2,3,4,5,6-hexamethylbenzenonium ion and the intermediate formation of the 2,3,4,5,6-pentamethylbenzyl cation, which is capable of entering into further oxidative transformations leading to substitution of the hydrogen atom in two and three methyl groups.The structure of the final products from the observed transformations were established, and a mechanism is proposed for their formation.

Elektrochemicl Oxidation of Organic Compounds in Fluorosulfuric Acid. IV. Voltammetric Investigation of the Formation and of the Anodic Behaviour of Some Benzyl Cations and Arenium Ions

The anodic behaviour of a series of benzylic alcohols, ethers or acetates 1 - 10, benzyl cyanides 11 - 21 and aromatic hydrocarbons 22 - 35 is investigated by cyclic voltammetry in fluorosulfuric acid at -76 deg C.The oxidation of the benzyl cations ArCH2(+) formed from a part of the benzylic compounds leads at potentials by 0,7 to 0,8 V more positive than those of the neutral compounds with addition of SO3F(-) to stable cation radicals ArCH2OSO2F(+.).In a further oxidation step another CH3-group is functionalized to CH2OSO2F.The anodic peak potentials of the arenium ions are by about 1.1 V more positive than those of the nonprotonated hydrocarbons. The dissociation equilibrium of ArCH2OSO2F and the protonation equilibrium of the hydrocarbons are discussed in terms of the donor ability of the aromatic compounds at borderline cases.