3470-91-5

Usage

Organic compound

Contains a chlorine atom, an amine group, and a hydroxyl group 1-chloro-3-[(2-methoxyphenyl)amino]propan-2-ol is classified as an organic compound because it contains carbon atoms bonded to hydrogen, as well as other elements like chlorine, nitrogen, and oxygen.

Pharmaceutical industry use

Chiral reagent for the synthesis of various drugs 1-chloro-3-[(2-methoxyphenyl)amino]propan-2-ol is used as a chiral reagent in the pharmaceutical industry, which helps in the synthesis of different drugs with specific three-dimensional structures.

Intermediate in organic synthesis

Production of other organic compounds 1-chloro-3-[(2-methoxyphenyl)amino]propan-2-ol also serves as an intermediate in the production of other organic compounds, making it a useful building block in organic chemistry.

Versatile reagent

Presence of amino and hydroxyl groups The presence of both an amine group and a hydroxyl group in the molecule makes 1-chloro-3-[(2-methoxyphenyl)amino]propan-2-ol a versatile reagent for various organic synthesis reactions.

Importance in industries

Diverse applications in pharmaceutical and chemical industries 1-chloro-3-[(2-methoxyphenyl)amino]propan-2-ol is an important chemical with a wide range of applications in both the pharmaceutical and chemical industries, making it a valuable compound for research and development.

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 106-89-8 epichlorohydrin 

Relevant academic research and scientific papers

Switchable synthesis of cyclic carbamates by carbon dioxide fixation at atmospheric pressure

The base-promoted switchable synthesis of five- and six-membered cyclic carbamates using atmospheric pressure carbon dioxide as the C1 source was developed. The chemoselectivity of products was simply controlled by changing bases and solvents. The reaction proceeds effectively under mild conditions, affording valuable cyclic carbamates. Experimental results and DFT studies revealed the reaction mechanism.

Selective biocatalytic aminolysis of (±)-epichlorohydrin: Synthesis and ICAM-1 inhibitory activity of (S)-(+)-3-arylamino-1-chloropropan-2-ols

Regio- and enantioselective synthesis of (S)-(+)-3-arylamino-1- chloropropan-2-ols has been achieved by the epoxide ring opening of (±)-epichlorohydrin with different aromatic amines in the presence of Candida rugosa lipase. Activities of seven model (S)-

Mild and efficient synthesis of β-amino alcohols by antimony trichloride catalysed opening of epoxides

Nucleophilic opening of epoxides with aniline derivatives in the presence of catalytic amount of antimony trichloride in acetonitrile at room temperature afford the corresponding β-amino alcohols in excellent to very good yield.

Efficient synthesis of β-amino alcohols catalyzed by niobium pentachloride: Regioselective ring opening of epoxides with aromatic amines

Epoxides undergo a rapid ring-opening reaction with aromatic amines catalyzed by niobium pentachloride under mild reaction conditions. All the reactions were carried out at room temperature to afford the corresponding β-amino alcohols in excellent yields

Potassium dodecatungstocobaltate trihydrate (K5CoW 12O40·3H2O) as an efficient catalyst for aminolysis of epoxides

Aminolysis of epoxides using various amines was catalyzed with potassium dodecatungstocobaltate trihydrate in a convenient and efficient method with good selectivities.