Cas 347184-59-2,ethyl 2-[3-(9-chloro-3-methyl-4-oxo-5H-isoxazolo[4,3-c]quinolin-5-yl)cyclohexyl]acetate

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Check Digit Verification of cas no

The CAS Registry Mumber 347184-59-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,7,1,8 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 347184-59:
(8*3)+(7*4)+(6*7)+(5*1)+(4*8)+(3*4)+(2*5)+(1*9)=162
162 % 10 = 2
So 347184-59-2 is a valid CAS Registry Number.

347184-59-2Upstream product

14318-64-0 ethyl (3-nitrophenyI)acetate

347184-59-2Downstream Products

347184-59-2Relevant articles and documents

Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)

Norman, Bryan H.,Lander, Peter A.,Gruber, Joseph M.,Kroin, Julian S.,Cohen, Jeffrey D.,Jungheim, Louis N.,Starling, James J.,Law, Kevin L.,Self, Tracy D.,Tabas, Linda B.,Williams, Daniel C.,Paul, Donald C.,Dantzig, Anne H.

, p. 5526 - 5530 (2007/10/03)

Structure-activity relationship (SAR) studies on the tricyclic isoxazole series of MRP1 modulators have resulted in the identification of potent and selective inhibitors containing cyclohexyl-based linkers. These studies ultimately identified compound 21b

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347184-59-2