347189-47-3

Upstream product

• 347189-36-0 7-(tert-butyldimethylsilyloxy)-9-(tert-butyldiphenylsilyloxy)-4-triethylsilyloxynonan-1-ol 
• 347189-37-1 7-(tert-butyldimethylsilyloxy)-9-(tert-butyldiphenylsilyloxy)-4-triethylsilyloxynonal 
• 347189-35-9 7-(tert-butyldimethylsilyloxy)-9-(tert-butyldiphenylsilyloxy)-4-triethylsilyloxynon-2-ene 
• 347189-34-8 7-(tert-butyldimethylsilyloxy)-9-(tert-butyldiphenylsilyloxy)non-1-en-4-ol 
• 347189-32-6 4-(tert-butyldimethylsilyloxy)-6-(tert-butyldiphenylsilyloxy)hexan-1-ol 
• 347189-33-7 4-(tert-butyldimethylsilyloxy)-6-(tert-butyldiphenylsilyloxy)hexanal 
• 347189-31-5 1-(tert-butyldiphenylsilyloxy)-3-(tert-butyldimethylsilyloxy)hex-5-ene 
• 347189-30-4 (±)-1-((tert-butyldiphenylsilyl)oxy)hex-5-en-3-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 127047-71-6 3-(tert-butyldiphenylsilyloxy)propan-1-ol 
• 112897-03-7 3-(tert-butyldiphenylsilyloxy)-1-propanal 
• 347189-38-2 1,11-bis-(tert-butyldimethylsilyloxy)-13-(tert-butyldiphenylsilyloxy)-8-triethylsilyloxytridec-3-yn-5-ol 

Downstream Products

• 347189-49-5 1-(tert-butyldiphenylsilyloxy)-5-(1,6-dioxaspiro[4.5]dec-9-en-2-yl)-pentan-3-ol 
• 347189-48-4 4-{5-[5-(tert-butyldiphenylsilyloxy)-3-hydroxypentyl]-2-methoxytetrahydrofuran-2-yl}but-3-yn-1-ol 

Relevant academic research and scientific papers

Synthesis of the novel 1,7,9-trioxadispiro[4.1.5.2]-tetradecane ring system present in the spirolides

A synthesis of bis-spiroacetal 13 which constitutes the bis-spiroacetal moiety of the complex marine biotoxins, spirolides 1 and 2 is described. The synthetic strategy adopted is based on assembly of a suitably protected acyclic hydroxyketone precursor. K