347190-57-2Relevant academic research and scientific papers
Mimicking Enzymes: Asymmetric Induction inside a Carbamate-Based Steroidal Cleft
Concellón, Carmen,Martín, Judith,Gallegos, Miguel,Fanjul-Mosteirín, Noé,Costales, Aurora,Pendás, ángel Martín,Del Amo, Vicente
, p. 3994 - 3997 (2019/06/17)
Cholic acid has been elaborated into a carbamate-based tripodal architecture, which is able to promote an asymmetric organic transformation inside its chiral cavity. The nature of this steroidal catalyst has been disclosed by quantum-chemical calculations. It comprises the preorganization and confinement of the reagents within the cavity of the steroid to form a supramolecular complex held together by means of cooperative H-bond contacts. This operational mode resembles that of some enzymes.
One-pot synthesis of new carbamate-type molecular tweezers derived from deoxycholic acid under microwave irradiation
Zhao, Zhi-Gang,Liu, Xing-Li,Chen, Yu,Shi, Zhi-Chuan
experimental part, p. 481 - 484 (2010/12/25)
A rapid, safe, and efficient method for the preparation of new carbamate type molecular tweezers based on deoxycholic acid was reported. Eleven new molecular tweezers have been synthesised in good yield(91-96%). The structures of these receptors were conf
