34737-39-8Relevant articles and documents
A short access to (+)-ptilocaulin
Cossy, Janine,BouzBouz, Samir
, p. 5091 - 5094 (1996)
A short access to (+)-ptilocaulin involving a photoreductive cyclopropane ring opening of an optically active bicyclo(4.1.0)heptanone derivative is described.
Preparation of o-Fluorophenols from Nonaromatic Precursors: Mechanistic Considerations for Adaptation to Fluorine-18 Radiolabeling
Yasui, Norio,Mayne, Christopher G.,Katzenellenbogen, John A.
supporting information, p. 5540 - 5543 (2015/12/01)
The preparation of fluorine-18 labeled o-fluorophenols at high specific activity is challenging and requires use of [18F]fluoride ion as the radioisotope source. As a novel, alternative approach, we found that treatment of α-diazocyclohexenones with Selectfluor and Et3N·3HF followed by HF elimination and tautomerization afforded o-fluorophenols regioselectively and rapidly. To adapt this chemistry to 18F radiolabeling, using bromine electrophiles in place of Selectfluor gave the o-fluorophenol via an α-bromo-α-fluoroketone intermediate in lower but still reasonable yields.
Copper/palladium-catalyzed 1,4 reduction and asymmetric allylic alkylation of α,β-unsaturated ketones: Enantioselective dual catalysis
Nahra, Fady,Mace, Yohan,Lambin, Dominique,Riant, Olivier
, p. 3208 - 3212 (2013/04/23)
Cooperative efforts: The catalytic coupling of the two organometallic intermediates is possible through a Cu/Pd-based dual catalysis (see scheme; LG=leaving group), in which the CuI catalytic cycle generates catalytically the starting material
