347377-92-8

Basic information

• Product Name: germacra-1(10),4,11(13)-trien-12-oic acid
• Synonyms: germacra-1(10),4,11(13)-trien-12-oic acid
• CAS NO: 347377-92-8
• Molecular Formula: C15H22O2
• Molecular Weight: 234.34
• Mol File: 347377-92-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: germacra-1(10),4,11(13)-trien-12-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: germacra-1(10),4,11(13)-trien-12-oic acid(347377-92-8)
• EPA Substance Registry System: germacra-1(10),4,11(13)-trien-12-oic acid(347377-92-8)

Safety Data

• Hazardous Substances Data: 347377-92-8(Hazardous Substances Data)

Upstream product

• 28028-64-0 (R)-(+)-germacrene A 

Downstream Products

• 3650-43-9 β-costic acid 
• 69978-82-1 2-((2R,4aR)-4a,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl)acrylic acid 
• 28399-17-9 (+)-Eudesma-3,11⁽¹³⁾-dien-12-oic acid 

Relevant articles and documents

Hydroxylation of sesquiterpenes by enzymes from chicory (Cichorium intybus L.) roots

A microsomal enzyme preparation of chicory roots catalyses the hydroxylation of various sesquiterpene olefins in the presence of NADPH. Most of these hydroxylations take place at an isopropenyl or isopropylidene group. The number of products obtained from any of the substrates is confined to one or, in a few cases, two sesquiterpene alcohols. In addition, the conversion of (+)-valencene into nootkatone through β-nootkatol was observed. The involvement of (+)-germacrene A hydroxylase (a cytochrome P450 enzyme) and other enzymes of sesquiterpene lactone biosynthesis in these reactions is discussed.