347389-74-6

Usage

Uses

Used in Organic Synthesis:
2-Ethynyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane is used as a reagent in organic synthesis for its ability to form robust carbon-boron bonds, which is crucial in creating complex organic molecules.
Used in Pharmaceutical and Agrochemical Development:
In the pharmaceutical and agrochemical industries, 2-Ethynyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane serves as a building block, leveraging its bond-forming properties to construct molecules with desired therapeutic or pesticidal properties.
Used in Optoelectronic Device Manufacturing:
2-Ethynyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane is used as a component in the production of OLEDs (organic light-emitting diodes) and other optoelectronic devices, where its chemical properties contribute to the performance and efficiency of these technologies.
Used in Research:
Due to its stability and safety profile, 2-Ethynyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane is widely used in research settings, allowing scientists to explore new chemical reactions and applications in a controlled and manageable manner.

Upstream product

• 6730-96-7 2,3-dimethyl-2,3-butanediol bis(trimethylsilyl) ether 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 70277-75-7 lithium acetylide 

Downstream Products

• 374715-22-7 3-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole 
• 365564-05-2 1,3,5-tris(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene 
• 480425-35-2 methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 171364-80-0 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 910875-11-5 methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trimethylsilyl)benzoate 
• 910875-08-0 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trimethylsilyl)benzoate 
• 653589-95-8 2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzoic acid methyl ester 
• 919197-88-9 3,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine 
• 1002334-13-5 1-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1002334-12-4 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1160614-68-5 5-methyl-1-(4-nitrophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1160614-69-6 5-isopropyl-1-(4-nitrophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1160614-72-1 2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine 
• 1396123-91-3 1-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole 

Relevant academic research and scientific papers

Boronate Ester Bullvalenes

Boronate ester bullvalenes are now accessible in two to four operationally simple steps. This unlocks late-stage diversification through Suzuki cross-coupling reactions to give mono-, di-, and trisubstituted bullvalenes. Moreover, a linchpin strategy enab

Regioselective synthesis of multisubstituted benzenes by palladium-catalyzed intermolecular reaction of β-iodo-β-silylstyrenes with alkynes

The Pd-catalyzed reaction between β-iodo-β-silylstyrenes and terminal alkynes in i-Pr2NEt gave 1,2,3,5-tetrasubstituted benzenes with complete regioselection. The use of certain silylacetylenes as alkynes enabled efficient synthesis of 1,3,5-trissilyl-2-arylbenzenes, which could be transformed into other multisubstituted benzenes by displacement of the silyl groups.

Cobalt(I)-mediated preparation of polyborylated cyclohexadienes: Scope, limitations, and mechanistic insight

A series of 1,3- and 1,4-di-boryl-1,3-cyclohexadiencs have been prepared by intermolecular CoCp-mediated [2+2+2] cocyclizations of alkynylboronic pinacolate esters with alkenes, followed by oxidative demetallation with iron(III) chloride. The effect of su

Boron-directed regio- and stereoselective enyne cross metathesis: Efficient synthesis of vinyl boronate containing 1,3-dienes

(Chemical Equation Presented) Regio- and stereoselective enyne cross metathesis reactions between borylated alkynes and terminal alkenes were realized to provide a variety of functionalized vinyl boronates. High chemical yield and regioselectivity was ach