347390-20-9Relevant articles and documents
DNA-Decorated Two-Dimensional Crystalline Nanosheets
Albert, Shine K.,Sivakumar, Irla,Golla, Murali,Thelu, Hari Veera Prasad,Krishnan, Nithiyanandan,Joseph Libin,Ashish,Varghese, Reji
supporting information, p. 17799 - 17802 (2017/12/26)
Design and synthesis of high aspect ratio 2D nanosheets with surface having ultradense array of information-rich molecule such as DNA is extremely challenging. Herein, we report a universal strategy based on amphiphilicity-driven self-assembly for the crafting of high aspect ratio, 2D sheets that are densely surface-decorated with DNA. Microscopy and X-ray analyses have shown that the sheets are crystalline. The most unique feature of the sheets is DNA-directed surface addressability, which is demonstrated through the decoration of either faces of the sheet with gold nanoparticles through sequence-specific DNA hybridization. Our results suggest that this design strategy can be applied as a general approach for the synthesis of DNA decorated high aspect ratio sheets, which may find potential applications in materials science, drug delivery, and nanoelectronics.