Dichlorofluorescein sodium salt is a synthetic dye characterized by its unique fluorescence properties and solubility in various solvents. It exhibits weak yellow fluorescence when slightly soluble in water, turning orange, and displays green yellow fluorescence when soluble in ethanol. Additionally, it appears pink with yellow fluorescence in acetone and undergoes a color change in concentrated sulfuric acid, turning titian and then yellow brown upon dilution, with orange precipitation. The dye's aqueous solution turns red upon the addition of sodium hydroxide. Dichlorofluorescein sodium salt shares similar dye characteristics with C.I. 45370 and demonstrates good dispersibility in glycerol and paraffin.
3474-67-7
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Basic information
- Product Name: dichlorofluorescein sodium salt
- Synonyms: dichlorofluorescein sodium salt
- CAS NO:3474-67-7
- Molecular Formula: C20H10 Cl2 O5 . 2 Na
- Molecular Weight: 425.19
- EINECS: N/A
- Product Categories: N/A
- Mol File: 3474-67-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: dichlorofluorescein sodium salt(CAS DataBase Reference)
- NIST Chemistry Reference: dichlorofluorescein sodium salt(3474-67-7)
- EPA Substance Registry System: dichlorofluorescein sodium salt(3474-67-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3474-67-7(Hazardous Substances Data)
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3474-67-7 Usage
Uses
Used in Research and Diagnostic Applications:Dichlorofluorescein sodium salt is used as a fluorescent probe for detecting oxidative stress, reactive oxygen species (ROS), and nitric oxide (NO) in biological systems. Its fluorescence properties allow for the monitoring of these molecules, which are crucial in various cellular processes and can indicate the presence of certain diseases or conditions.
Used in Analytical Chemistry:
In analytical chemistry, dichlofluorescein sodium salt serves as a sensitive and selective reagent for the detection and quantification of trace metal ions, such as iron, copper, and zinc. Its fluorescence properties enable the development of assays and sensors for accurate and reliable measurements in various samples.
Used in Environmental Monitoring:
Dichlorofluorescein sodium salt is employed as an indicator dye for monitoring water quality and pollution. Its ability to react with various contaminants and change color or fluorescence intensity allows for the assessment of environmental conditions and the detection of potential hazards.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, dichlorofluorescein sodium salt is utilized as a marker for drug delivery and release studies. Its fluorescence properties facilitate the tracking of drug molecules within the body, providing valuable information on drug distribution, metabolism, and efficacy.
Used in Cosmetics Industry:
Dichlorofluorescein sodium salt is used as a color additive in the cosmetics industry, where its unique fluorescence properties can enhance the appearance of products and provide visual appeal to consumers.
Preparation
2-Chlorobenzene-1,3-diol (1 Moore) and Phthalic anhydride (1 Moore) condensation, its product again with 2-Chlorobenzene-1,3-diol??condensation, and then into sodium salt.Check Digit Verification of cas no
The CAS Registry Mumber 3474-67-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,7 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.Calculate Digit Verification of CAS Registry Number 3474-67:
(6*3)+(5*4)+(4*7)+(3*4)+(2*6)+(1*7)=97
97 % 10 = 7
So 3474-67-7 is a valid CAS Registry Number.
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dichlorofluorescein sodium salt
