34773-01-8 Usage
Uses
Used in Organic Synthesis:
DTABI is utilized as a reagent in organic synthesis for its ability to efficiently participate in the creation of a wide variety of organic compounds. Its versatility makes it a valuable tool in the synthesis of pharmaceuticals and natural products, contributing to the development of new medicines and chemical entities.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, DMABI is employed as a building block for the synthesis of complex molecules. Its unique structure and reactivity are harnessed to construct indanone, indane, and indene derivatives, which are integral to the development of novel therapeutic agents.
Used in Chemical Biology:
DTABI's potential in chemical biology is recognized for its role in drug discovery and development. Its properties make it a candidate for probing biological systems and understanding the mechanisms of action of various compounds, thereby aiding in the advancement of new pharmaceuticals.
Used in Pharmaceutical Industry:
Within the pharmaceutical industry, DMABI is used as a key intermediate in the synthesis of drug candidates. Its contribution to the construction of complex molecular frameworks is essential for the development of innovative treatments and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 34773-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,7,7 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 34773-01:
(7*3)+(6*4)+(5*7)+(4*7)+(3*3)+(2*0)+(1*1)=118
118 % 10 = 8
So 34773-01-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO/c1-13(2)8-10-7-9-5-3-4-6-11(9)12(10)14/h3-6,8H,7H2,1-2H3/b10-8-
34773-01-8Relevant academic research and scientific papers
A copper-catalyzed three component reaction of aryl acetylene, sulfonyl azide and enaminone to form iminolactone via 6π electrocyclization
Sun, Jiarui,Cheng, Xiangsheng,Mansaray, John Kamanda,Fei, Weihong,Wan, Jieping,Yao, Weijun
supporting information, p. 13953 - 13956 (2019/01/03)
We developed a copper-catalyzed three component reaction of aryl acetylene, enaminone and sulfonyl azide to construct iminolactone via a cascade process involving copper-catalyzed alkyne-azide cycloaddition (CuAAC), Michael addition of metalated ketenimin
Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: Effects of lipophilicity and structure-activity relationships
Altomare, Cosimo,Cellamare, Saverio,Summo, Luciana,Catto, Marco,Carotti, Angelo,Thull, Ulrike,Carrupt, Pierre-Alain,Testa, Bernard,Stoeckli-Evans, Helen
, p. 3812 - 3820 (2007/10/03)
A number of condensed pyridazines and pyrimidines were synthesized and tested for their monoamine oxidase-A (MAO-A) and MAO-B inhibitory activity. Their lipophilicity was examined by measuring partition coefficients and RP- HPLC capacity factors, revealin
2-Aminomethyleneindanone analgesic agents
-
, (2008/06/13)
Novel 2-aminomethyleneindanones having analgesic activity are disclosed.