34776-79-9Relevant academic research and scientific papers
SIMPLE PREPARATION OF METHYL 4-CHLOROMETHYL- AND METHYL 5-CHLOROMETHYL-2-THIOPHENECARBOXYLATE
Kozmik, Vaclav,Palecek, Jaroslav
, p. 1483 - 1486 (2007/10/02)
Selective reduction of a mixture of methyl 4-chloromethyl-2-thiophenecarboxylate (I) and the 5-chloromethyl isomer II, prepared by chloromethylation of methyl 2-thiophenecarboxylate (III), gave pure 4-chloromethyl derivative I and 5-methyl-2-thiophenecarboxylate (V) which on treatment with sulfuryl chloride was converted into the 5-chloromethyl isomer II.
