34785-00-7

Upstream product

• 92089-09-3 2-Methyl-4-(2-nitrophenyl)-5-oxo-1,4,5,7-tetrahydrofuro<3,4-b>pyridin-3-carbonsaeuremethylester 
• 67035-22-7 nifedipine 
• 21829-25-4 nifedipine 
• 88434-69-9 2,6-Dimethyl-4-(2-nitro-phenyl)-1-oxy-pyridine-3,5-dicarboxylic acid dimethyl ester 
• 14205-39-1 methyl (E)-3-aminocrotonate 
• 87191-97-7 3-<(2-Nitrophenyl)methylene>-2,4(3H,5H)-furandione 
• 105378-60-7 2-Acetoxymethyl-6-methyl-4-(2-nitrophenyl)-pyridin-3,5-dicarbonsaeuredimethylester 
• 113817-49-5 N-<2-methyl-3,5-dimethoxycarbonyl-4-(o-nitrophenyl)-1,4-dihydropyridinyl-6-methyl>pyridinium bromide 

Downstream Products

• 34783-31-8 2-Hydroxymethyl-5-methoxycarbonyl-6-methyl-4-(2-nitrophenyl)-pyridin-3-carbonsaeure 
• 105378-62-9 2-Methyl-4-(2-nitrophenyl)-5-oxo-5,7-dihydrofuro<3,4-b>pyridin-3-carbonsaeure 

Relevant academic research and scientific papers

Cyclic hydroxamic acids of the phenanthridine type - Synthesis and investigation of lipoxigenase inhibition

The synthesis of the benzo[f]furo[3,4-c] [2,7]naphthyridines 15 and 17, the thieno[2,3-c] [2,7]naphthyridines 21 as well as the pyrimido[5,4-c]quinoline 25 is described. These compounds and the structurally related diaza- and triaza-phenanthrenes 3-8 were

FORMATION OF FURO- AND DIFURO-1,4-DIHYDROPYRIDINES IN THE BROMINATION OF 2,6-DIMETHYL-3,5-DIMETHOXYCARBONYL-4-(o-NITROPHENYL)-1,4-DIHYDROPYRIDINE

Furo- and difuro-1,4-dihydropyridines were obtained by bromination of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-nitrophenyl)-1,4-dihydropyridine with mild brominating agents (pyridinium bromide perbromide, N-bromosuccinimide, and dioxane dibromide).

Independent synthesis and hydrolysis of the side metabolite from nifedipine

The hydrolysis of the title compound, obtained by Boekelheide rearrangement of the N-oxide 1b, is investigated.