347886-08-2

Upstream product

• 3970-21-6 2-Methoxyethoxymethyl chloride 
• 347886-06-0 (1'S,2'S,4S)-4-benzyl-3-[5-benzyloxymethyl-2'-(1'-hydroxyethyl)-5-hexenoyl]oxazolidin-2-one 
• 113964-32-2 1-{[2-((chloromethyl)allyl)oxy]methyl}-4-methoxybenzene 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 347886-02-6 5-benzyloxymethyl-5-hexenoic acid ethyl ester 
• 347886-20-8 5-benzyloxymethyl-hex-5-enoic acid 
• 347886-00-4 [2-(bromomethyl)prop-2-en-1-yloxy]methylbenzene 
• 347886-04-8 (S)-4-benzyl-3-(5-benzyloxymethyl-5-hexenoyl)oxazolidin-2-one 

Downstream Products

• 347886-09-3 (1'R,2S)-5-benzyloxymethyl-2-[1'-(2-methoxyethoxymethoxy)ethyl]-5-hexenoic acid 
• 347886-10-6 (1'R,2S)-5-benzyloxymethyl-2-[1'-(2-methoxyethoxymethoxy)ethyl]-5-hexenoic acid S-ethyl ester 

Relevant academic research and scientific papers

A tandem metal carbene cyclization-cycloaddition approach to the pseudolaric acids

An approach toward the synthesis of the antifungal and cytotoxic pseudolaric acids based on the tandem metal carbene cyclization-cycloaddition reaction is described. Using this strategy, the advanced intermediate 3a bearing three of the four stereocenters

A rhodium carbene cyclization-cycloaddition cascade strategy toward the pseudolaric acids.

A rhodium carbene intramolecular cyclization-cycloaddition cascade was employed as the key reaction in the synthesis of the nucleus of the cytotoxic diterpenoids pseudolaric acids A and B.