34790-80-2Relevant academic research and scientific papers
Inhibitory effect of novel tetrahydropyrimidine-2(1H)-thiones on melanogenesis
Thanigaimalai,Lee, Ki-Cheul,Bang, Seong-Cheol,Lee, Jee-Hyun,Yun, Cheong-Yong,Roh, Eunmiri,Hwang, Bang-Yeon,Kim, Youngsoo,Jung, Sang-Hun
experimental part, p. 1135 - 1142 (2010/04/24)
The series of imidazoldine-2-thiones 2 and tetrahydropyrimidine-2-thiones 3 were discovered as inhibitor of α-MSH-induced melanin production in melanoma B16 cells. The primary bioassay showed that 1-(4-ethylbenzyl)-tetrahydropyrimidine-2(1H)-thione 3e (>1
Regioselectivity in The Reductive Formation of Dihydro-5-halo-2(1H)-pyrimidinones
Rise, Frode,Undheim, Kjell
, p. 195 - 202 (2007/10/02)
5-Chloro-2(1H)-pyrimidinones are reduced by lithium tri-tert-butoxyaluminum hydride to dihydropyrimidinones.Pyrimidines with a substituent capable of conjugation gave the dihydro isomer which has its double bond in conjugation with this substituent.In the
