3480-93-1Relevant academic research and scientific papers
Synthesis of a sensitive and selective potassium-sensing fluoroionophore
Carpenter, Richard D.,Verkman
supporting information; experimental part, p. 1160 - 1163 (2010/05/18)
"Chemical Equation Presented" An efficient synthesis is reported that delivers in 5 steps and 52% overall yield a new structurally simplified fluorescent K+ sensor with improved K+ sensitivity and selectivity over existing K+ sensors. The synthesis procedure utilizes a new template-directed oxidative C-N bond-forming macrocyclization reaction and reports new approaches to Pd(O), Sandmeyer-like and metal-free aminoarylations, as well as organotitanium additions to vinylogous sulfonates.
Reductive monoalkylation of aromatic and aliphatic nitro compounds and the corresponding amines with nitriles
Nacario, Ruel,Kotakonda, Shailaja,Fouchard, David M. D.,Tillekeratne, L. M. Viranga,Hudson, Richard A.
, p. 471 - 474 (2007/10/03)
(Chemical Equation Presented) A simple, selective, rapid, and efficient procedure for the synthesis of secondary amines from the reductive alkylation of either aliphatic or aromatic nitro compounds and the corresponding amines is reported. Ammonium formate is used as the hydrogen source and Pd/C as the hydrogen transfer catalyst. The reaction is carried out at room temperature. The rate differences for the preferential formation of secondary over tertiary products are due to both steric and electronic factors.
Phospha-adamantanes as ligands for organopalladium chemistry: Aminations of aryl halides
Gerristma, David,Brenstrum, Timothy,McNulty, James,Capretta, Alfredo
, p. 8319 - 8321 (2007/10/03)
The use of Pd2dba3·CHCl3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha-adamantane has been shown to facilitate the effective amination of aryl halides with aromatic or aliphatic amines in high yields.
USE OF HEXAMETHYLPHOSPHORAMIDE (HMPA) IN THE ALKYLATION OF AROMATIC AMINES
Juaristi, Eusebio,Reyna, J. Daniel
, p. 3521 - 3524 (2007/10/02)
The convenience of using HMPA as solvent in the mono and dialkylation of anilines was demonstrated through the study of the reaction of p-toluidine with alkyl halides, tosylates and epoxides.
