34836-69-6Relevant academic research and scientific papers
Inhibitory effect of novel tetrahydropyrimidine-2(1H)-thiones on melanogenesis
Thanigaimalai,Lee, Ki-Cheul,Bang, Seong-Cheol,Lee, Jee-Hyun,Yun, Cheong-Yong,Roh, Eunmiri,Hwang, Bang-Yeon,Kim, Youngsoo,Jung, Sang-Hun
experimental part, p. 1135 - 1142 (2010/04/24)
The series of imidazoldine-2-thiones 2 and tetrahydropyrimidine-2-thiones 3 were discovered as inhibitor of α-MSH-induced melanin production in melanoma B16 cells. The primary bioassay showed that 1-(4-ethylbenzyl)-tetrahydropyrimidine-2(1H)-thione 3e (>1
1-(Substituted benzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidones: A series with stimulant and depressant activities
Ellis,Schwan,Wessels,Miles
, p. 1194 - 1198 (2007/10/02)
A series of 1-(substituted benzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidones was synthesized primarily by catalytic hydrogenation of the corresponding 1-(substituted benzyl)-2(1H)-pyrimidone. The pharmacological evaluation of these compounds in mice revealed a
