348575-88-2

Basic information

• Product Name: Optovin
• Synonyms: Optovin;5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone;Oprovin
• CAS NO: 348575-88-2
• Molecular Formula: C15H13N3OS2
• Molecular Weight: 315.41322
• Product Categories: Inhibitors
• Mol File: 348575-88-2.mol

Chemical Properties

• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Soluble in DMSO (up to 30 mg/ml)
• PKA: 7.65±0.50(Predicted)
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
• CAS DataBase Reference: Optovin(CAS DataBase Reference)
• NIST Chemistry Reference: Optovin(348575-88-2)
• EPA Substance Registry System: Optovin(348575-88-2)

Safety Data

• Hazardous Substances Data: 348575-88-2(Hazardous Substances Data)

Usage

Uses

Used in Neuroscience Research:
Optovin is used as a research tool for studying the activation of TRPA1 channels in sensory neurons. Its application is crucial in understanding the role of these channels in photodetection and their involvement in motor behaviors.
Used in Pharmaceutical Development:
Optovin serves as a potential candidate for the development of new drugs targeting TRPA1 channels, which may have therapeutic applications in various conditions related to sensory neuron function and motor behavior regulation.
Used in Optogenetics:
In optogenetics, Optovin is used as a means to control and manipulate the activity of specific neurons in living organisms. By activating TRPA1 channels, researchers can study the effects of these channels on motor behaviors and other neuronal functions in a controlled manner.
Used in Drug Screening and Testing:
Optovin is utilized in drug screening and testing processes to identify potential modulators of TRPA1 channels. This helps in the development of new therapeutic agents that can target these channels for various medical applications.

References

1) Kokel?et al. (2013),?Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol.,?9?257