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General Description

2-Amino-3-nitrobiphenyl is a chemical compound with the molecular formula C12H10N2O2. It is an aromatic amine with a nitro group attached to one of the benzene rings. This chemical is classified as a Group 2A carcinogen by the International Agency for Research on Cancer (IARC) and is considered to be a potential human carcinogen. It is primarily used in research and experimental purposes to study its carcinogenic effects and its potential as a mutagen. Exposure to 2-Amino-3-nitrobiphenyl has been linked to an increased risk of developing bladder and liver cancer, and it is important to handle and use this chemical with extreme caution in a laboratory setting.

Upstream product

• 615-43-0 2-iodophenylamine 
• 13331-27-6 m-nitrobenzene boronic acid 
• 5570-18-3 2-aminophenylboronic acid 
• 615-36-1 2-bromoaniline 

Downstream Products

• 1330574-31-6 ethyl 2-(5,6-dihydro-9-nitro-5-tosylphenanthridin-6-yl)acetate 
• 1312448-07-9 N-Ts-2-(3'-nitrophenyl)aniline 
• 81316-79-2 2-nitrotriphenylene 
• 81316-78-1 1-nitrotriphenylene 
• 289480-22-4 trans-4-[9-ethyl-6-(3-nitro-phenylamino)-9H-purin-2-yl-amino]cyclohexanol 

Relevant academic research and scientific papers

Intramolecular Remote C-H Activation via Sequential 1,4-Palladium Migration to Access Fused Polycycles

An unprecedented intramolecular remote C-H activation via sequential 1,4-palladium migration with an aromatic ring as a conveyor has been described. This reaction provides an efficient route to construct diverse polycyclic frameworks in moderate to good yield via palladium-catalyzed remote C-H activation/alkene insertion, arylation, alkenylation, and the Heck reaction. The preliminary mechanistic studies revealed that the 1,4-palladium migration process was reversible.

An Active Palladium Colloidal Catalyst for the Selective Oxidative Heterocoupling of (Hetero)Aryl Boronic Acids

A highly selective oxidative heterocoupling protocol for (hetero)aryl boronic acids with an active palladium colloidal catalyst was developed. The judicious choice of electronically different aryl boronic acids made possible such couplings under mild conditions, with air as oxidant, while embracing a wide substrate scope. This successful approach further allowed the development of a unique one-pot sequential oxidative heterocoupling/Suzuki–Miyaura cross-coupling tandem process for accessing substituted terphenyls.

Derivative of triaromatic amines and organic electroluminescence device thereof

The invention discloses a derivative of triaromatic amines and organic electroluminescent device thereof, which relates to the technical field of organic photoelectric material, the derivative of triaromatic amines provided by the invention has bipolar structure, which has good carrier transport characteristics so that electrons and holes can be effectively combined in the luminescent layer, the luminescent efficiency is high. In addition, the derivative of triaromatic amines provided by the invention has relatively high vitrification temperature and thermal stability, which is helpful for material film formation. The electroluminescence device provided by the invention includes a cathode, an anode and one or more organics layers, at least one organic layer contains derivatives of triaromatic amines provided by the invention, the organic electroluminescence device provided by the invention has relatively low driving voltage, relatively high luminous efficiency and luminosity and relatively long service life.

Aromatic amine derivative and organic light-emitting device thereof

The invention provides an aromatic amine derivative and an organic light-emitting device thereof, and relates to the technical field of organic photoelectric materials. The aromatic amine derivative has a bipolar structure, so the aromatic amine derivativ

Palladium-catalyzed interannular meta-C-H arylation

The interannular meta-selective C-H arylation of biaryl-2-trifluoroacetamides using Pd(ii)/norbornene catalysis is reported. The installation of a trifluoroacetyl protecting group to tune their electronic properties and binding ability is essential for in

Synthesis of Triphenylenes Starting from 2-Iodobiphenyls and Iodobenzenes via Palladium-Catalyzed Dual C-H Activation and Double C-C Bond Formation

A novel and facile approach for the synthesis of triphenylenes has been developed via palladium-catalyzed coupling of 2-iodobiphenyls and iodobenzenes. The reaction involves dual palladium-catalyzed C-H activations and double palladium-catalyzed C-C bond formations. A range of unsymmetrically functionalized triphenylenes can be synthesized with the reaction. The approach features readily available starting materials, high atom- and step-economy, and access to various unsymmetrically functionalized triphenylenes.

Pd-catalyzed sequential C-C and C-N bond formations for the synthesis of N-heterocycles: Exploiting protecting group-directed C-H activation under modified reaction conditions

Easy & efficient: A Pd-catalyzed domino olefination/conjugate addition reaction of N-Ts-2-arylanilines with activated olefins has been achieved at ambient temperature under the newly defined reaction conditions. This process highlighted the directing effect of the N-protecting group in C-H activation, displayed broad substrate scope with wide functional group compatibility; thus rendering a straightforward entry to a wide variety of N-heterocycles such as dihydrophenanthridines.

Efficient synthesis of phenanthridines using Hendrickson reagent initiated cascade reaction under mild conditions

A number of variously substituted phenanthridines have been synthesized using the newly developed methodology under mild conditions. The Hendrickson reagent initiated cascade annulation, which is composed of a mild conversion of stable amide precursor to highly reactive imido-carbonium intermediate and a subsequent intramolecular Friedel-Crafts reaction, successfully served as the key method. Georg Thieme Verlag Stuttgart New York.