348624-25-9Relevant academic research and scientific papers
Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: Design, synthesis, and evaluation as topically applied, dermal anti-scarring agents
Bailey, Simon,Fish, Paul V.,Billotte, Stephane,Bordner, Jon,Greiling, Doris,James, Kim,McElroy, Andrew,Mills, James E.,Reed, Charlotte,Webster, Robert
scheme or table, p. 6562 - 6567 (2009/09/30)
Succinyl hydroxamates 1 and 2 are disclosed as novel series of potent and selective inhibitors of procollagen C-proteinase (PCP) which may have potential as anti-fibrotic agents. Carboxamide 7 demonstrated good PCP inhibition and had excellent selectivity
PROCOLLAGEN C-PROTEINASE INHIBITORS
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, (2008/06/13)
and their salts, solvates, prodrugs, etc., wherein the substituents have the values mentioned herein, are Procollagen C-Proteinase (PCP) inhibitors and have utility in conditions mediated by PCP.
