349-01-9

Basic information

• Product Name: 2,4-DINITRO-5-FLUOROTOLUENE
• Synonyms: 2,4-DINITRO-5-FLUOROTOLUENE;1-fluoro-5-methyl-2,4-dinitrobenzene;2,4-Dinitro-5-fluorotoluene 99%;2,4-Dinitro-5-fluorotoluene99%;5-FLUORO-2,4-DINITROTOLUENE;2,4-Dinitro-5-fluorotolene;2,4-Dinitro-1-fluoro-5-methylbenzene;2,4-Dinitro-5-methylfluorobenzene
• CAS NO: 349-01-9
• Molecular Formula: C₇H₅FN₂O₄
• Molecular Weight: 200.12
• Product Categories: Halogen toluene
• Mol File: 349-01-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 82°C
• Boiling Point: 319 °C at 760 mmHg
• Flash Point: 146.8 °C
• Appearance: /
• Density: 1.497 g/cm³
• Vapor Pressure: 0.000649mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 2,4-DINITRO-5-FLUOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DINITRO-5-FLUOROTOLUENE(349-01-9)
• EPA Substance Registry System: 2,4-DINITRO-5-FLUOROTOLUENE(349-01-9)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22
• Safety Statements: 36/37/39-45
• Hazardous Substances Data: 349-01-9(Hazardous Substances Data)

Usage

General Description

2,4-DINITRO-5-FLUOROTOLUENE is a chemical compound with the molecular formula C7H5N3O4F. It is a yellow crystalline solid commonly used as an intermediate in the manufacturing of dyes, pigments, and pharmaceuticals. It is also used in organic synthesis and as a building block for various chemical reactions. However, it is important to handle this chemical with caution as it is considered hazardous and may cause irritation to the eyes, skin, and respiratory system. It should be stored and handled in accordance with proper safety protocols to minimize the risk of exposure and potential harm.

InChI:InChI=1/C7H5FN2O4/c1-4-2-5(8)7(10(13)14)3-6(4)9(11)12/h2-3H,1H3

Upstream product

• 352-70-5 m-Fluorotoluene 

Downstream Products

• 141922-20-5 4-fluoro-6-methyl-benzene-1,3-diamine 
• 952665-28-0 (E)-2-(5-fluoro-2,4-dinitrophenyl)-N,N-dimethylethenamine 
• 3606-21-1 5-methoxy-2,4-dinitrotoluene 
• 1307309-23-4 O₂-(2,4-dinitro-5-methylphenyl) 1-[(4-ethoxycarbonyl)homopiperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1307309-22-3 O₂-(2,4-dinitrophenyl-5-methyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl] diazen-1-ium-1,2-diolate 
• 121729-10-0 [2-(5-fluoro-2,4-dinitro-phenyl)-vinyl]-dimethyl-amine 
• 1338223-20-3 1-(5-methyl-2.4-dinitro-phenylamino)-3-(3-trifluoromethyl-phenoxy)-propan-2-one O-methyl-oxime 
• 110600-91-4 diethyl 5-fluoro-2,4-dinitrobenzoylmalonate 
• 110600-93-6 ethyl 3-cyclopropylamino-2-(5-fluoro-2,4-dinitrobenzoyl)acrylate 
• 110600-95-8 ethyl 3-cyclopropylamino-2-(5-hydroxy-2,4-dinitrobenzoyl)acrylate 
• 110600-92-5 ethyl 5-fluoro-2,4-dinitrobenzoylacetate 
• 393-92-0 5-fluoro-2,4-dinitrobenzoyl chloride 

Relevant articles and documents

COMPOUNDS OF 3-(5-SUSTITUTED OXY-2, 4-DINITROPHENYL)-2-OXO-PROPIONIC ACID ESTER, SYNTHESIS AND APPLICATIONS THEREOF

Synthesis of the novel compound 3 (3-(5-substituted Oxy-2,4-dinitro-phenyl)-2-oxo-propionic acid ester) to make Pyrroloquinoline quinone (PQQ) and using it for pharmaceutical purposes is described. More specifically, this disclosure relates to synthesizing the PQQ in an efficient method by using a novel intermediate Formula 1 resulting in a shorter process and higher yield of PQQ. A unique process to make sodium compound of PQQ using either sodium hydroxide and/or sodium carbonate is also shown.

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.