349-67-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Methoxy-5-(trifluoromethyl)phenol is used as an intermediate in the synthesis of pharmaceuticals for its ability to enhance lipophilicity and metabolic stability, which are crucial for drug discovery and development. 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL aids in the creation of more effective and stable medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Methoxy-5-(trifluoromethyl)phenol serves as an intermediate in the production of agrochemicals, leveraging its properties to improve the effectiveness and stability of these compounds, thereby contributing to more efficient pest control and crop protection.
Used in Material Science:
2-Methoxy-5-(trifluoromethyl)phenol is utilized in material science applications for its potential to modify the properties of materials, such as enhancing their stability and performance in various environments. Its unique structure allows for the development of new materials with specific characteristics tailored for different uses.
It is important to handle and use 2-Methoxy-5-(trifluoromethyl)phenol with care, as it may pose hazards if not properly managed, underscoring the need for safety precautions in its application across industries.

Upstream product

• 240139-82-6 (2-methoxy-5-(trifluoromethyl)phenyl)boronic acid 
• 402-52-8 methyl 4-(trifluoromethyl)phenyl ether 

Downstream Products

• 645-08-9 Isovanillic acid 
• 579-79-3 1-methoxy-2,5-bis-(4-nitro-benzoyloxy)-4-trifluoromethyl-benzene 
• 366-10-9 4-nitro-benzoic acid-(2-methoxy-5-trifluoromethyl-phenyl ester) 
• 344-67-2 2-methoxy-5-trifluoromethyl-hydroquinone 

Relevant academic research and scientific papers

HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL

The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (l)-(ll l) or Compounds (1 )-(65) of Table 1 ) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotropic lateral sclerosis, glaucoma, ischaemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome.

PHENOXIACETIC ACID DERIVATIVES

The invention relates to certain 2-substituted phenoxyacetic acid derivatives of formula (I), in which the variables are as defined in the claims, useful in the treatment of diseases or conditions in which modulation of the CRTh2 receptor is beneficial, s

New series of morpholine and 1,4-oxazepane derivatives as dopamine D 4 receptor ligands: Synthesis and 3D-QSAR model

Since the identification of the dopamine D43 receptor subtype and speculations about its possible involvement in schizophrenia, much work has been put into development of selective D4 ligands. These selective ligands may be effective antipsychotics without extrapyramidal side effects. This work describes the synthesis of a new series of 2,4-disubstituted morpholines and 2,4-disubstituted 1,4-oxazepanes with selectivity for the dopamine D4 receptor. A 3D-QSAR analysis using the GRID/GOLPE methodology was performed with the purpose to get a better understanding of the relationship between chemical structure and biological activity. Inspection of the coefficient plots allowed us to identify that regions which are important for affinity are situated around the two benzene ring systems, a p-chlorobenzyl group, and the aliphatic amine belonging to the morpholine or 1,4-oxazepane system. In addition, the size of the morpholine or 1,4-oxazepane ring seems to be important for affinity.