34904-46-6

Basic information

• Product Name: 1,2-dimethyl-1H-perimidine
• CAS NO: 34904-46-6
• Molecular Formula: C₁₃H₁₂N₂
• Molecular Weight: 196.2478
• Mol File: 34904-46-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 366.4°C at 760 mmHg
• Flash Point: 175.4°C
• Density: 1.15g/cm³
• Vapor Pressure: 1.47E-05mmHg at 25°C
• Refractive Index: 1.642
• CAS DataBase Reference: 1,2-dimethyl-1H-perimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dimethyl-1H-perimidine(34904-46-6)
• EPA Substance Registry System: 1,2-dimethyl-1H-perimidine(34904-46-6)

Safety Data

• Hazardous Substances Data: 34904-46-6(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Structure

Perimidine ring with two nitrogen atoms and two fused benzene rings

Usage

Organic synthesis and pharmaceutical research as a building block for complex molecules

Biological activities

Potential anti-cancer and anti-inflammatory properties

Physical state

Colorless to pale yellow liquid

Toxicity

Low toxicity

Safety precautions

Handle with care and caution due to potential health hazards

Upstream product

• 5157-10-8 2-methyl-1H-perimidine 
• 80-48-8 methyl p-toluene sulfonate 
• 479-27-6 naphthalene-1,8-diamine 
• 74-88-4 methyl iodide 

Downstream Products

• 73724-97-7 3-Amino-1,2-dimethylperimidin-3-ium mesitylenesulfonate 
• 20734-56-9 1,8-dimethylaminonaphthalene 

Relevant articles and documents

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Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors

For the development of novel anticancer agents, we designed and synthesized a total of 37 perimidine o-quinone derivatives containing the o-quinone group at the A or B ring and different substituents (alkyl groups, aryl groups or heterocycles) at the C ri

Poly(1,1-bis(dialkylamino)propan-1,3-diyl)s; Conformationally-controlled oligomers bearing electroactive groups

The design of polymers with repeating [C(NR2)2CH 2CH2] units which may simultaneously provide conformational control and contain repeating electroactive centres is discussed; (NR2)2 groups would be ideally provided by ortho-phenylenediamine derivatives, with 1,8-diaminonaphthalenes as alternatives. Oligomers containing 1,8-bis(methylamino)naphthalenes, up to the hexamer, were obtained by condensation of oligomers of CH3[COCH 2CH2]nCOCH3 with 1,8-bis(methylamino)naphthalene, but attempts to prepare related oligomers from 1,2-bis(alkylamino)benzenes were unsuccessful, as only terminal ketone groups could be converted to aminals. Evidence for a strong preference for all-anti conformations of the main chain in the naphthalenediamine oligomers is provided by ring current effects on 1H NMR shifts, and by X-ray structures, which also provide evidence of intercalation in the solid state. Electrochemical studies of these oligomers show irreversible oxidation of oligomers in solution, but oxidation of longer oligomers leads to the deposition of a reddish-pink insoluble material which shows two reversible oxidation waves. Possible interpretation of these results is discussed. The Royal Society of Chemistry 2009.