34906-44-0

Usage

Uses

Used in Chemical Research and Industry:
(3-Nitrobenzyl)triphenylphosphonium chloride is used as a reagent in various chemical reactions for its powerful nucleophilic properties, making it useful in a variety of substitution reactions.
Used in Organic Synthesis:
(3-Nitrobenzyl)triphenylphosphonium chloride is used as a versatile reagent in the synthesis of various compounds, particularly in the field of organophosphorus chemistry, due to its high stability and ease of handling.

Upstream product

• 603-35-0 triphenylphosphine 
• 619-23-8 3-Nitrobenzyl chloride 

Downstream Products

• 236754-28-2 ethyl 7-(3-nitrophenyl)-6-heptenoate 
• 236754-29-3 7-(3-aminophenyl)-1-heptanol 
• 878801-18-4 [(benzylsulfonyl)(3-nitrophenyl)methylene](triphenyl)phosphorane 
• 350827-76-8 cis-1-(2,4-dichlorophenyl)-2-(3-nitrophenyl)-ethylene 

Relevant academic research and scientific papers

Synthesis of novel sulfonyl-stabilized phosphorus ylides, and the kinetics and mechanism of their conventional and flash vacuum pyrolysis reactions

Nine substituted sulfonyl-stabilized phosphorus ylides were prepared by treating their intermediate ylide analogues with phenylmethanesulfonyl fluoride. The stoichiometric ratio of the reactants for each preparation needed to be adjusted according to the basicity of each ylide intermediate. The nine ylide compounds were then subjected to conventional (sealed-tube) gas-phase pyrolysis at 470-545 K. The pyrolytic reactions were homogeneous and obeyed a first-order rate equation. The values of the Arrhenius log A (s-1) and E a (kJ mol-1) obtained for these reactions averaged 11.12 ± 2.00 and 131.8 ± 24.4, respectively. Analysis of the pyrolysates from conventional pyrolysis and from flash vacuum pyrolysis at 600 K showed the products to be complex mixtures of triphenylphosphine, triphenylphosphine oxide, triphenylphosphine sulfide, and symmetric and unsymmetric alkenes. Conventional pyrolysis also gave novel mixed sulfones and, for the p-methoxyaryl substituent, p-anisaldehyde. The products of the reactions under study are explained on the basis of a mechanism involving a sulfonyl carbene intermediate, and the reaction mechanism is used to rationalize the kinetic results and molecular reactivities.

Dihydrofolate reductase inhibitors

A compound of formula (I) or (II), wherein X is hydrogen, halogen, alkyl, aralkyl,aryloxy, arylalkoxy or alkoxy, Y is hydrogen, halogen, alkyl, aralkyl, aryloxy, arylalkoxy or alkoxy, or formula (a) wherein A and B are different and one of A and B is CHs

Synthesis and Photocylization of some 4-(5)Arylethenylimidazoles

The synthesis of eleven 4-(5)arylethenylimidazoles and their separation into cis and trans isomers is described.Ir, uv, nmr, and mass spectrometric data of the compounds are given.The photocyclization of the unsubstituted and p-substituted compounds is reported.