34907-01-2

Basic information

• Product Name: Propanamide, 2-oxo-N-propyl- (9CI)
• Synonyms: Propanamide, 2-oxo-N-propyl- (9CI)
• CAS NO: 34907-01-2
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.15704
• Product Categories: ACETYLGROUP
• Mol File: 34907-01-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propanamide, 2-oxo-N-propyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, 2-oxo-N-propyl- (9CI)(34907-01-2)
• EPA Substance Registry System: Propanamide, 2-oxo-N-propyl- (9CI)(34907-01-2)

Safety Data

• Hazardous Substances Data: 34907-01-2(Hazardous Substances Data)

Upstream product

• 57383-89-8 C₇H₁₆N₄O₃ 
• 690242-28-5 2-methoxy-N-propylacrylamide 
• 74421-70-8 N-Propyl-2-hydroxypropanamide 
• 107-10-8 propylamine 

Relevant articles and documents

Reactions of heterocumulenes with organometallic reagents: XII. Reaction of metallated vinyl ethers with isocyanates: Ingenious synthesis of pyruvic acid amides

Acid hydrolysis of 2-alkoxy-N-substituted acrylamides easily obtained by reacting α-metallated vinyl ethers with isocyanates proceeded regiospecifically leading to the formation in a high yield of virtually undescribed and difficultly available 2-oxo-N-substituted propanamides.

Phosphoenolpyruvamides. Amide-Phosphate Interactions in Analogues of Phosphoenolpyruvate

Ethyl esters of nitrogen-substituted carboxamides of phosphoenolpyruvate (1 and 2) were obtained from the reactions of triethyl phosphite with the corresponding nitrogen-substituted 3-bromopyruvamide.The hydrolysis of the ethyl ester portions of 1 and 2 occurs with an observed first-order rate constant that is 4 orders of magnitude larger than is estimated for triethyl phosphate under comparable conditions, indicating that participation by the neighboring carboxamide group is occurring.However, the enol phosphate ester substituent is cleaved much more slowly than are vinyl phosphate esters.The results are consistent with a mechanism in which the amide adds to the adjacent phosphate to form a reactive cyclic intermediate.The data support the proposal that amides can become phosphorylated during process that involve interactions of peptides and nucleotides or during phosphate-transfer process.The hydrolysis products of 1 and 2 may also be useful analogues of phosphoenolpyruvate in studies of enzyme mechanisms and in the design of inhibitors.