349094-99-1Relevant academic research and scientific papers
Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: Design, synthesis, and evaluation as topically applied, dermal anti-scarring agents
Bailey, Simon,Fish, Paul V.,Billotte, Stephane,Bordner, Jon,Greiling, Doris,James, Kim,McElroy, Andrew,Mills, James E.,Reed, Charlotte,Webster, Robert
scheme or table, p. 6562 - 6567 (2009/09/30)
Succinyl hydroxamates 1 and 2 are disclosed as novel series of potent and selective inhibitors of procollagen C-proteinase (PCP) which may have potential as anti-fibrotic agents. Carboxamide 7 demonstrated good PCP inhibition and had excellent selectivity
