349132-14-5Relevant academic research and scientific papers
Stereocontrolled chemoenzymatic synthesis of 2,3-disubstituted piperidines
Monterde, Maria I.,Brieva, Rosario,Gotor, Vicente
, p. 525 - 528 (2001)
(R,R)-2,3-Disubstituted piperidines were readily synthesized starting from (R)-(+)-5-bromo-2-hydroxypentanenitrile (R)-2. An enantioselective (R)-oxynitrilase-catalyzed transcyanation was used to prepare the starting cyanohydrin (R)-2.
