349150-35-2Relevant academic research and scientific papers
Stereoselective Synthesis of Oxabicyclo[2.2.1]heptenes via a Tandem Dirhodium(II)-Catalyzed Triazole Denitrogenation and [3 + 2] Cycloaddition
Yuan, Hao,Gong, Jianxian,Yang, Zhen
, p. 5500 - 5503 (2016/11/17)
A novel synthetic strategy for the diastereoselective synthesis of structurally diverse oxabicyclo[2.2.1]heptenes has been developed, featuring a tandem reaction combining a Rh-catalyzed triazole denitrogenation and a novel type of [3 + 2] cycloaddition reaction. This tandem reaction was thought to proceed via a five-membered oxonium ylide intermediate, which was formed by the intramolecular nucleophilic attack of the carbonyl group on the α-imino metallocarbene followed by an inter- or intramolecular [3 + 2] dipolar cycloaddition with a range of alkynes and alkenes.
Synthesis of biaryl compounds using tandem ruthenium-catalyzed ring-closing metathesis
Yoshida, Kazuhiro,Shida, Hiroaki,Takahashi, Hidetoshi,Yanagisawa, Akira
supporting information; experimental part, p. 344 - 349 (2011/02/27)
Tandem ring-closing enyne metathesis (RCEM)/ring-closing olefin metathesis (RCM) of tetraenynes with Grubbs second-generation catalyst, followed by elimination, was found to be a new and efficient synthetic approach to biaryl compounds. A preliminary asymmetric version of this approach, which used homochiral Ru-alkylidene catalysts, is also presented. A ringing endorsement: Tandem ring-closing enyne metathesis (RCEM)/ring-closing olefin metathesis (RCM) of tetraenynes with the Grubbs second-generation catalyst followed by elimination, was found to be a new and efficient synthetic approach to biaryl compounds (see scheme). A preliminary asymmetric version of this approach is also presented.
An efficient catalytic protocol for the Pauson-Khand reaction
Blanco-Urgoiti, Jaime,Abdi, Delbrin,Domínguez, Gema,Pérez-Castells, Javier
, p. 67 - 74 (2008/09/16)
New experimental conditions have been developed for an efficient catalytic Pauson-Khand reaction. These are based on the use of a mixture of molecular sieves and tert-butanol as inducers of the process. This mixture, with the appearance of a paste, is abl
Tandem Enyne Metathesis-Diels-Alder Reaction for Construction of Natural Product Frameworks
Rosillo, Marta,Dominguez, Gema,Casarrubios, Luis,Amador, Ulises,Perez-Castells, Javier
, p. 2084 - 2093 (2007/10/03)
Enynes connected through aromatic rings are used as substrates for metathesis reactions. The reactivity of three ruthenium carbene complexes is compared. The resulting 1,3-dienes are suitable precursors of polycyclic structures via a Diels-Alder process.
Diastereoselective Pauson-Khand reactions on aromatic substrates
Blanco-Urgoiti, Jaime,Casarrubios, Luis,Domínguez, Gema,Pérez-Castells, Javier
, p. 3315 - 3317 (2007/10/03)
The synthesis of several natural products' frameworks is carried out by means of a diastereoselective intramolecular Pauson-Khand reaction promoted by molecular sieves. Diastereoselectivity is achieved only if a coordinating group is present at a convenie
