349150-82-9Relevant academic research and scientific papers
2-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2λ6-benzo [1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors
Apfel,Banner,Bur,Dietz,Hubschwerlen,Locher,Marlin,Masciadri,Pirson,Stalder
, p. 1847 - 1852 (2007/10/03)
Potent, selective, and structurally new inhibitors of the Fe(II) enzyme Escherichia coli peptide deformylase (PDF) were obtained by rational optimization of the weakly binding screening hit (5-chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-acetic acid hydra
1,5-Dihydroimidazoquinazolinones as blood platelet aggregation inhibitors
Kienzle,Kaiser,Chodnekar
, p. 547 - 556 (2007/10/02)
Syntheses of 1,5-dihydroimidazoquinazolinones and their activities as blood platelet aggregation inhibitors are described.
Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
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, (2008/06/13)
Optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-ones and 6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]-quinazolin-2-ones or the pharmaceutically acceptable salts thereof are compounds useful as blood platelet anti-aggregative and/or antihypertensive and/or bronchodilator agents in mammals, including humans.
