34935-83-6

Upstream product

• 936240-32-3 4-oxy-1,4-diaza-spiro[4.5]dec-3-en-2-one 
• 108-86-1 bromobenzene 
• 1369762-32-2 4-(2,4-dimethoxybenzyl)-3-oxo-2-phenyl-1,4-diazaspiro[4.5]dec-1-ene 1-oxide 
• 1369762-49-1 1-(2,4-dimethoxybenzyl)-1,4-diazaspiro[4.5]decan-2-one 
• 1369762-29-7 4-(2,4-dimethoxybenzyl)-3-oxo-1,4-diazaspiro[4.5]dec-1-ene 1-oxide 

Downstream Products

• 93045-16-0 3-phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one 

Relevant academic research and scientific papers

Palladium-catalyzed direct arylation of imidazolone N-oxides with aryl bromides and its application in the synthesis of GSK2137305

The palladium-catalyzed direct arylation of imidazolone N-oxides with aryl bromides to afford the corresponding 4-aryl imidazolone N-oxides is described. This method has been successfully used for the synthesis of GSK2137305.