349395-92-2Relevant academic research and scientific papers
Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N1-arylsulfonyl indole derivatives as 5-HT6 receptor ligands
Nirogi, Ramakrishna V.S.,Badange, Rajeshkumar,Kambhampati, Ramasastri,Chindhe, Anil,Deshpande, Amol D.,Tiriveedhi, Vinaykumar,Kandikere, Vishwottam,Muddana, Nageswararao,Abraham, Renny,Khagga, Mukkanti
, p. 7431 - 7435 (2012)
4-(Piperazin-1-yl methyl)-N1-arylsulfonyl indole derivatives were designed and synthesized as 5-HT6 receptor (5-HT6R) ligands. The lead compound 6a, from this series shows potent in vitro binding affinity, good PK profile,
