3494-85-7Relevant academic research and scientific papers
Synthesis of Substituted 2-Pyrrolidones
Neidlein, Richard,Shatzmiller, Shimon,Sinnreich, Dorina
, p. 8 - 12 (2007/10/02)
The preparation of the 2-pyrrolidone derivatives 6a,b via β-formyldicarboxylates 4a,b - starting from 1a,b and 2a,b - is described; reaction of 4a and 4b in ethanol in the presence of ammonium carbonate gave 5a and 6a,b, respectively. 6a was separated by chromatography into the isomers 7 and 8. 5a is also obtained by reaction of 4a in ethanol in the presence of p-toluenesulfonic acid; 5a in ethanol in the presence of ammonium carbonate at room temperature remained unchanged after 3 days.
