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349405-25-0

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349405-25-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 349405-25-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,9,4,0 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 349405-25:
(8*3)+(7*4)+(6*9)+(5*4)+(4*0)+(3*5)+(2*2)+(1*5)=150
150 % 10 = 0
So 349405-25-0 is a valid CAS Registry Number.

349405-25-0Downstream Products

349405-25-0Relevant articles and documents

Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors

Hou, Shaohua,Yang, Xiping,Yang, Yuejing,Tong, Yu,Chen, Quanwei,Wan, Boheng,Wei, Ran,Lu, Tao,Chen, Yadong,Hu, Qinghua

, (2021)

Apoptosis signal-regulating kinase 1 (ASK1, MAP3K5), a member of the mitogen-activated protein kinase (MAPK) signaling pathway, is involved in cell survival, differentiation, stress response, and apoptosis. ASK1 kinase inhibition has emerged as a promisin

PYRIDINYLQUINAZ0LINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS

-

Page/Page column 73, (2010/11/30)

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

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