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2-(4-bromophenyl)-N-(tert-butyl)acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

349415-66-3

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349415-66-3 Usage

Type of compound

Organic compound

Derivative

Acetamide derivative

Contains

Bromophenyl group, tert-butyl group

Usage

Pharmaceutical research, building block for organic synthesis, drug development, medicinal chemistry

Pharmacological properties

Potential activity modification on biological targets

Reagent

Can introduce specific functional groups into organic molecules

Check Digit Verification of cas no

The CAS Registry Mumber 349415-66-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,9,4,1 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 349415-66:
(8*3)+(7*4)+(6*9)+(5*4)+(4*1)+(3*5)+(2*6)+(1*6)=163
163 % 10 = 3
So 349415-66-3 is a valid CAS Registry Number.

349415-66-3Downstream Products

349415-66-3Relevant academic research and scientific papers

A convenient synthesis of N-tert-butyl amides by the reaction of di-tert-butyl dicarbonate and nitriles catalyzed by Cu(OTf)2

Yang, Wanfeng,Feng, Chengliang,Tang, Yuqi,Ji, Min,Chen, Junqing

, p. 602 - 608 (2020)

The utility of Cu(OTf)2 as the catalyst for the synthesis of a series of N-tert-butyl amides in excellent isolated yields via the reaction of nitriles (alkyl, aryl, benzyl, and furyl nitriles) with di-tert-butyl dicarbonate is described. Cu(OTf)2 is a highly stable and efficient catalyst for the present Ritter reaction under solvent-free conditions at room temperature.

An efficient synthesis of N-tert-butyl amides by the reaction of tert-butyl benzoate with nitriles catalyzed by Zn(ClO4)2·6H2O

Feng, Cheng-Liang,Yan, Bin,Zhang, Min,Chen, Jun-Qing,Ji, Min

, p. 535 - 542 (2019/02/12)

An efficient, mild and inexpensive synthesis of N-tert-butyl amides from the reaction of nitriles (aryl, benzyl and sec-alkyl nitriles) with tert-butyl benzoate catalyzed by the employment of 2?mol% Zn(ClO4)2·6H2O at 50?°C

Iodine-catalyzed one-pot synthesis of amides from nitriles via Ritter reaction

Theerthagiri, Palani,Lalitha, Appaswami,Arunachalam, Pirama Nayagam

supporting information; experimental part, p. 2813 - 2819 (2010/07/04)

Ritter reactions of alcohols and tert-butyl acetate with various nitriles were performed using iodine as a mild and effective catalyst under heating conditions to afford the corresponding amides in good to excellent yields.

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