349553-94-2 Usage
Uses
Used in Analytical Chemistry:
7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 is used as an internal standard for the quantification of 7α-hydroxy cholesterol by GC/MS or LC/MS. It aids in the accurate measurement of cholesterol and oxysterol levels, which are crucial for understanding various biological processes and conditions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 is used as a research tool to study the role of oxysterols in the biosynthesis of bile acids, such as cholic acid (CA) and chenodeoxycholic acid (CDCA). Understanding these processes can lead to the development of new therapeutic strategies for conditions related to cholesterol metabolism and bile acid synthesis.
Used in Cell Biology Research:
7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 is employed in cell biology research to investigate the effects of oxysterols on cellular processes. For instance, it has been shown to increase levels of adhesion molecules (ICAM-1, VCAM-1, and E-selectin) in human umbilical vein endothelial cells (HUVECs) and to enhance the secretion of chemokine (C-C motif) ligand 2 (CCL2) and matrix metalloproteinase-9 (MMP-9) in serum-deprived THP-1 cells. These studies contribute to a better understanding of the role of oxysterols in cellular signaling and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 349553-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,9,5,5 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 349553-94:
(8*3)+(7*4)+(6*9)+(5*5)+(4*5)+(3*3)+(2*9)+(1*4)=182
182 % 10 = 2
So 349553-94-2 is a valid CAS Registry Number.
