349636-50-6Relevant articles and documents
Synthesis of heterocycle substituted 1-aryl-4-piperidones
Hu, Baihua,Malamas, Michael,Ellingboe, John
, p. 857 - 870 (2002)
A series of heterocycle substituted 1-aryl-4-piperidones were prepared via Knoevenagel condensations between nitrogen-containing 5-membered heterocycles and benzaldehyde (1) followed by reduction or amination. The oxadiazolidinedione ring was formed by reacting the N-hydroxyurea (10) with methyl chloroformate and sodium hydride.